|
週次 |
日期 |
單元主題 |
|
第1週 |
|
Introduction to the Lecture |
|
第2週 |
|
Structural and Chemical Properties of Biological Macromolecules |
|
第3週 |
|
Protein Crystallography |
|
第4週 |
|
Principle of Nuclear Magnetic Resonance Spectroscopy |
|
第5週 |
|
Biomolecular NMR technique |
|
第6週 |
|
Applications of Modern NMR Spectroscopy |
|
第7週 |
|
Biophysical Methods to Probe Non-covalent Molecular Interaction (I):Circular Dichroism, UV and Fluorescence Spectroscopy |
|
第8週 |
|
Biophysical Methods to Probe Non-covalent Molecular Interaction (II):Surface Plasmon Resonance and ITC |
|
第9週 |
|
Mid-term |
|
第10週 |
|
Structural Basis of Signal Transduction and Post-translation Modification |
|
第11週 |
|
Molecular Enzymology |
|
第12週 |
|
Protein/peptide interaction with membrane |
|
第13週 |
|
Structural Features of Receptors and ligands |
|
第14週 |
|
Structural View of Protein-DNA Recognition in Gene Regulation |
|
第15週 |
|
Analytical Ultracentrifugation |
|
第16週 |
|
Molecular Docking and Bioinformatics Approach |
|
第17週 |
|
Strategies for Drug Discovery, Rational Drug Design versus Drug screen |